Podcast CME Course Information

Exam: Exam 157

Issue: November 20, 2012

Learning Objectives

PRRT2 mutations in familial infantile seizures, paroxysmal dyskinesia and hemiplegic migraine

PRRT2 gene mutations: From paroxysmal dyskinesia to episodic ataxia and hemiplegic migraine

Upon completion of this podcast, the participant will be familiar with common clinical presentations of PRRT2 mutations.

Recommended Audience

This program is designed for physicians who are involved in providing patient care and who wish to advance their current knowledge of clinical medicine.

Core Competencies

• Medical Knowledge

Disclosures

Program Accreditation and Development Subcommittee (PADS) is responsible for reviewing and evaluating all CME programs. PADS members: Pradeep K. Sahota MD, FAAN, has nothing to disclose, Allison Brashear MD, FAAN, has received personal compensation for activities with Allergan, Merz, Ipsen and Osmotica as a consultant, has received personal compensation in an editorial capacity for Wemove, has received research support from Allergan, Merz, and Ipsen, J. Clay Goodman MD, FAAN, has nothing to disclose, Steven L. Lewis MD, FAAN, has received personal compensation in an editorial capacity for the journal Neurology, Barbara F. Westmoreland MD, FAAN, has nothing to disclose, Susan Rodmyre, has nothing to disclose.

Robert A. Gross, MD, PhD, FAAN has received research funding from the Department of the Army and UCBPharma. He is supported for educational endeavors from the University of Rochester Medical Center’s Clinical and Translational Science Award from the NIH. Dr. Gross has conducted clinical trials over the past five years funded by GlaxoSmithKline, UCB, Ortho-McNeil, Pfizer, and Marinus. He has served on the speakers’ bureaus for Abbott, UCB, and GlaxoSmithKline and has received consultant fees from GlaxoSmithKline and Harris Interactive. Since his appointment as Editor-in-Chief, Dr. Gross has ceased participation in industry-sponsored clinical trials and speakers’ bureaus. He receives an honorarium from AAN as Editor-in-Chief of Neurology.

Dr. Ted Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (35% effort); and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals. AAN staff members editing the test (P Baskin, L Kleffman) have no disclosures. The CME Journal Editors who have reviewed the exam are Steven Lewis, MD, who receives a stipend in his editorial capacity for Neurology and as an Associate Editor for Continuum: Lifelong Learning in Neurology; has received royalties for the books 'Field Guide to the Neurologic Examination' and 'Neurology for the Non-Neurologist;' and anticipates receiving royalties for the book 'Neurologic Disorders due to Systemic Disease;' and James WM Owens Jr. MD PhD, who receives royalties from UpToDate, Waltham, MA; grant support from NIH (PI, K08NS054882); and a stipend in his editorial capacity for Neurology.

Dr. Waugh serves on the editorial board of the Journal of Pediatric Biochemistry. Dr. Guerrini serves as an Associate Editor for Epilepsia, serves on the editorial boards for Seizure, BMC Medical Genetics, Topics in Epilepsy, Journal of Pediatric Epilepsy, Epileptic Disorders and European Neurological Journal, serves on the International Advisory Board for Progress in Epileptic Disorders; has received honoraria from Biocodex, UCB, Eisai Inc, ValueBox, Viropharma and EMA (European Medicine Agency), received funding for travel from Japanese Epilepsy Society and Weill Cornell Medical College; receives research support from the Italian Ministry of Health, the European Community Sixth Framework Thematic Priority Life Sciences, Genomics and Biotechnology for Health, the Italian Ministry of Education, University and Research, the Tuscany Region, the Telethon Foundation, and the Mariani Foundation; receives royalties for the books: Epilepsy and Movement disorders, Aicardi’s Epilepsy in children, Progress in epileptic spasms and West syndrome, Epilepsy and migraine, The causes of epilepsy and Dravet syndrome. Dr. Gardiner receives research support from The Muscular Dystrophy Campaign. Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Weathers receives honoraria as an AAN speaker.

The other participants had nothing to disclose.

CME Expiration

CME expires three years after publication date or sooner if podcasts are deemed out of date by reviewers.

Accreditation

The American Academy of Neurology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA PRA Credit™

The American Academy of Neurology designates that participants will receive 0.5 AMA PRA Category 1 CME credits™ by answering the multiple-choice questions in the online Podcast quiz.

Copyright

The American Academy of Neurology holds copyright for all materials in this exam.

Confidentiality

Any information regarding the identity of individuals taking the exam or their exam scores will be kept confidential.

Hardware and Software Requirements

A computer with a web browser such as Internet Explorer, Firefox, Safari, or Google Chrome is required.

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