The Circadian and Homeostatic Control of Sleep

Integrated Neuroscience Session

Thursday, April 30, 2:00–6:00 p.m.

The regulation of sleep and wake states is a major function of the nervous system, affecting multiple neurological systems in health and disease. Sleep and circadian rhythms play vital roles in refining neural function, including enhancements of memory and general health. This program includes lectures on recent advances in neurobiology of circadian and sleep regulation—from genes to disorders. These lectures will be complemented by research presentations, including posters, focused on the disorders of circadian rhythm, sleep stage dyscontrol, and sleep deprivation.

• 2:00–2:05 p.m. Introduction
• 2:05–2:30 p.m. Circadian Rhythms: Central Nervous System and Beyond, Phyllis C. Zee, MD, PhD
• 2:30–2:55 p.m. Novel Insights from Genetics and Molecular Characterization of the Human Clock, Louis Ptacek, MD, FAAN
• 2:55–3:20 p.m. Homeostatic Regulation of Sleep, TBD
• 3:20–3:30 p.m. Question and Answer Period

• IN5-1.001 Chicken or egg: Analysis of the association between headache and sleep disorders, Timothy M. Quast, MD
• IN5-1.002 Armodafinil Sustains Wakefulness Throughout the Day in Patients with Excessive Sleepiness Associated with Narcolepsy, Russell Rosenberg, MD
• IN5-1.003 The Underlying Sleep Disorder of Fibromyalgia and Chronic Fatigue Syndrome have Narcoleptiform Characterisitics: Results of Sleep Studies and HLA Markers, A. Robert Spitzer, MD
• IN5-1.004 CSF hypocretine-1 concentrations correlate with the level of fatigue in multiple sclerosis patients, Konrad Rejdak, MD, PhD
• IN5-1.005 Decreased sleep efficiency and increased daytime somnolence in Parkinson's disease subjects with hallucinations, Jennifer G. Goldman, MD
• IN5-1.006 Circadian Rhythms in the Vegetative State, Tristán A. Bekinschtein
• IN5-1.007 Preliminary observations of weather-related ambient atmospheric pressure changes on sleep-disordered breathing, Michael J. Doherty, MD
• IN5-1.008 A Case Study Of Fatal Insomnia (FI) With Clinical, Laboratory, And Genetic Findings, Jin Jun Luo, MD
• IN5-1.009 Resolution of amenorrhea and postmenopausal state after CPAP therapy for obstructive sleep apnea: Case Report, Nicolas Saikali, MD
• IN5-1.010 Restless Arms Syndrome, Walter O. Arruda, MD, MSc

• IN5-2.001 The Sleeping Brain?s Influence on Verbal Memory: Boosting Resistance to Interference, Jeffrey M. Ellenbogen, MMSc, MD
• IN5-2.002 Melanopsin-Containing Retinal Ganglion Cells and Circadian Phototransduction Are Spared by Neurodegeneration in Mitochondrial Optic Neuropathies, Chiara La Morgia, MD
• IN5-2.003 Circadian control of neural excitability in an animal model of temporal lobe epilepsy, Sachin Subhash Talathi, PhD
• IN5-2.004 Early pathology in sleep studies of patients with familial Creutzfeldt-Jakob Disease, Gili Givaty, MD
• IN5-2.005 REM Behavior Disorder associated with SOD1 Familial ALS, Sandra Donkervoort, MS
• IN5-2.006 Clinical presentation and acute treatment of electrical status epilepticus in sleep and sleep potentiated spikes, Yaman Z. Eksioglu, MD, PhD