Abstract Details

Title Integrated MRI and [11C]-PBR28 PET Imaging to Characterize In vivo Glial Activation in Amyotrophic and Primary Lateral Sclerosis: Cross Sectional and Longitudinal Study

Topic Neuromuscular and Clinical Neurophysiology (EMG)

Presentation(s) P2 - (-)

Poster/Presentation
Number 032

Background

Objective

Design/Methods

Results

Conclusions

Authors/Disclosures
Mohamad J. Alshikho, MD (Massachusetts General Hospital) PRESENTER	No disclosure on file
	No disclosure on file
	No disclosure on file
	No disclosure on file
Beverly Reynolds	Beverly Reynolds has nothing to disclose.
	No disclosure on file
	No disclosure on file
	No disclosure on file
Caterina Mainero, MD, PhD (Massacgusetts General Hospital)	The institution of Dr. Mainero has received research support from Genentech.
	No disclosure on file
	No disclosure on file
Suma Babu, MD, MPH (Massachusetts General Hospital, Brigham, Harvard)	The institution of Dr. Babu has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for OrphAI therapeutics. The institution of Dr. Babu has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. The institution of Dr. Babu has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Uniqure Therapeutics. Dr. Babu has received personal compensation in the range of $5,000-$9,999 for serving on a Speakers Bureau for Medscape. The institution of Dr. Babu has received research support from Biogen. The institution of Dr. Babu has received research support from Novartis. The institution of Dr. Babu has received research support from Ionis. The institution of Dr. Babu has received research support from OrphAI therapeutics. The institution of Dr. Babu has received research support from Denali Therapeutics. Dr. Babu has a non-compensated relationship as a Appointed Member of the Committee on ALS: Accelerating Treatments and Improving Quality of Life with National Academies of Sciences, Engineering and Medicine that is relevant to AAN interests or activities.
Sabrina Paganoni, MD, PhD	Dr. Paganoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cytokinetics. Dr. Paganoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Jannsen. Dr. Paganoni has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arrowhead. Dr. Paganoni has received personal compensation in the range of $0-$499 for serving as a Consultant for Sola. Dr. Paganoni has received personal compensation in the range of $0-$499 for serving as a Consultant for Frequency Therapeutics. The institution of Dr. Paganoni has received research support from Amylyx. The institution of Dr. Paganoni has received research support from Revalesio. The institution of Dr. Paganoni has received research support from Alector. The institution of Dr. Paganoni has received research support from UCB. The institution of Dr. Paganoni has received research support from Biohaven. The institution of Dr. Paganoni has received research support from Clene. The institution of Dr. Paganoni has received research support from Prilenia. The institution of Dr. Paganoni has received research support from Seelos. The institution of Dr. Paganoni has received research support from Calico. The institution of Dr. Paganoni has received research support from Denali. The institution of Dr. Paganoni has received research support from Anelixis. The institution of Dr. Paganoni has received research support from Cytokinetics.
	No disclosure on file
Nazem Atassi, MD	Dr. Atassi has received personal compensation for serving as an employee of Sanofi. Dr. Atassi has stock in Sanofi.