Log In

Forgot Password?

OR

Not a member? Continue as a nonmember.

Become a Member

By becoming a member of the AAN, you can receive exclusive information to help you at every stage of your career. Benefits include:

Join Now See All Benefits

Loading... please wait

Abstract Details

Polysomnography and Neuroendocrine Hormones in Subjective Cognitive Impaired Patients with Transformed Migraine
Headache
Headache Posters (7:00 AM-5:00 PM)
145
Migraine is associated with multiple comorbidities like depression, anxiety, poor sleep quality, and subjective cognitive impairment (SCI). This study aimed to evaluate the SCI and its relationship with anxiety, depression, neuroendocrine hormones (NEH), and sleep architecture in patients with transformed migraine (TM).  

This study aimed to evaluate the subjective cognitive impairment (SCI) and its relationship with anxiety, depression, neuroendocrine hormones (NEH), and sleep architecture in patients with transformed migraine (TM).  

The study conducted on 120 TM participants and 41 control group (CG). The subjective cognitive decline questionnaire classified the participants into SCI and non-SCI. The headache impact test-6, migraine disability assessment, montreal cognitive assessment, mini-mental state examination, patient health questionnaire-9, pittsburgh sleep quality index, Epworth sleeping scale, full polysomnography, NEH, Beck’s Anxiety, and depression inventory used and analyzed between the SCI and NSCI.
TM patients with SCI represent 34.2% with severe headache impact, disability, pain severity, more depressed, and anxious. They showed shorter sleep duration during weekdays, lowered sleep quality, lesser sleep time, efficiency, REM percent, more sleep latency, periodic limb movement, arousal index, snore index, and NREM3 percent. In addition, they experienced higher dysfunction of NEH. There is a positive correlation between with certain polysomnography parameters like NREM3 percent, sleep period, sleep index, sleep latency, sleep arousal index, and periodic limb movements, while inversely correlated with REM percent of total sleep time, total sleep time, and sleep efficiency. 
TM patients with SCI had more hormonal changes, sleep, and psychological disturbances. 
Authors/Disclosures
Mohammed A. ElSherif, MD, PhD, FAAN (Mansoura University)
PRESENTER
Dr. ElSherif has nothing to disclose.
Mohamed Abdelsalam (Mansoura University) Mohamed ABDELSALAM has nothing to disclose.
Amr Shoukri Amr Shoukri has nothing to disclose.
Ahmed Esmael No disclosure on file