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Abstract Details

Venous Thromboembolism Development in Stroke Patients: A Retrospective Analysis of Predictors
Cerebrovascular Disease and Interventional Neurology
P10 - Poster Session 10 (8:00 AM-9:00 AM)
Venous thromboembolism (VTE), which includes acute deep vein thrombosis (DVT) and pulmonary embolism (PE), is a complication among hospitalized stroke patients. The incidence varies with recent rates of 2.8% risk of developing VTE amongst Get with the Guidelines-Stroke registry (GWTG-S). Our aim was to identify risk factors of VTE in our institution.
As the incidence of VTE in stroke patients grows, we need to look for approaches to decrease these rates. Our retrospective study aims to characterize the population based on our Get With The Guidelines – Stroke (GTWG-S) registry that were reported to have strokes and subsequently developed VTE during admission and identify significant risk factors associated with VTE to improve outcomes for these patients.
A retrospective review of ischemic and hemorrhagic stroke patients that developed VTE after admission was performed. We excluded patients with chronic DVT or PE, superficial venous thrombus, arterial thrombus, or line associated DVT. Univariate and multivariate regression analysis was performed to identify factors that were significantly associated with VTE in our population.

From 2011-2018, a total of 6,018 patients were reported to have strokes. Of this population, 57 patients (0.9%) developed VTE during their hospital course. The mean age was 62 years, 59.6% were male, and admission NIHSS was 15.4. On univariate regression analysis, a high admission NIHSS (p <0.001), not receiving DVT prophylaxis by day 2 (p = 0.0012), hemorrhagic stroke (p <0.0001), and history of atrial fibrillation (p <0.05) were associated with development of VTE. On multivariate regression analysis, high NIHSS (p <0.0001), hemorrhagic stroke (p = 0.0028) and atrial fibrillation (p = 0.025) were associated with risk of VTE.

VTE is a significant contributor of morbidity and mortality. Stroke patients with high NIHSS on admission, hemorrhagic stroke, and history of atrial fibrillation are at high risk of VTE during hospitalization. 

Youssra H. Saqr, MD (OSU)
Dr. Saqr has nothing to disclose.
Hera A. Kamdar, MD Dr. Kamdar has nothing to disclose.
No disclosure on file
Archana Hinduja, MD Dr. Hinduja has nothing to disclose.