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Abstract Details

Neurological Manifestations in Post Renal Transplant Patients at Sindh Institute of Urology and Transplantation, Pakistan
General Neurology
P5 - Poster Session 5 (11:45 AM-12:45 PM)
Neurological complications are a significant cause of morbidity and mortality worldwide in patients who undergo solid organ transplants. Approximately one-third of SOT (solid organ transplant) patients will experience a neurological complication. This study was conducted in the largest kidney transplant center of Pakistan. 

 To assess the incidence and various types of neurological disorders seen in post renal transplant patients in a tertiary care hospital.

A single-center cross sectional study was done on renal transplant patients who developed neurological complications while being admitted or as outpatients from October 2017- January 2022 at SIUT. After ERB approval, data was collected in a standardized format while excluding out patients with psychiatric illness. Statistical analysis was carried out on SPSS version 20.

Total of 327 patients over a period of 4 years and 3 months were reviewed. Age range was 8-61+years, with mean age of 38 years; and majority were males (n229, 70%). Most common cause of renal transplant was unknown in 176 (52.6%). patients. Onset of neurological symptoms was mostly seen between 1-5 years after transplant. Most common presenting complaint was headache (n96, 29.4%) and seizures (n82, 25.1%).Most common neurological diagnosis was peripheral neuropathy (n85, 26%) followed by CNS infections (n49, 15%) and then epilepsy (n47, 14.4%). Along with low dose steroids, 235 patients were given azathioprine followed by cyclosporine [n111] as immunosuppressant.

Peripheral Neuropathy and CNS infections were leading neurological complications after renal transplant while most common symptoms were found to be headaches and seizures.

Mughis Sheerani, MD (Neurogym )
Dr. Sheerani has nothing to disclose.
Sadia Nishat, MBBS, FCPS (Sindh Institute of Urology and Transplantation) Dr. Nishat has nothing to disclose.