Log In

Forgot Password?


Not a member? Continue as a nonmember.

Become a Member

By becoming a member of the AAN, you can receive exclusive information to help you at every stage of your career. Benefits include:

Join Now See All Benefits

Loading... please wait

Abstract Details

Outcomes of Multiple Sclerosis Patients following Admission for Acute Ischemic Stroke in the United States
Cerebrovascular Disease and Interventional Neurology
P14 - Poster Session 14 (11:45 AM-12:45 PM)
While MS can influence various pathways in the body, there is a lack of research on the impact the disease has on outcomes following an AIS.

To understand the characteristics of Multiple Sclerosis (MS) patients admitted for Acute Ischemic Stroke (AIS) and any differences in outcomes.

The 2019 National Inpatient Sample (NIS) was queried to explore the characteristics and outcomes of MS patients admitted for AIS. 

Our study found 2100 (0.4%) AIS patients who also had a diagnosis of MS. More MS patients were females (70.2%), while non-MS patients were more likely to be males (50.8%) (p<0.05). Both groups comprised a higher proportion of patients classified as White (75.4% among MS cases and 67.9% among non-MS cases, p<0.05). MS patients also had a lower prevalence of old myocardial infarct (6.4% vs. 7.5%), but it was not statistically significant (p=0.066). We also found that MS patients were less likely to be diabetic (34.4% vs. 39.3%), hypertensive (77.4% vs. 86.1%), and hyperlipidemia (55.7% vs. 60.8%) compared to non-MS cases of AIS. However, more MS patients with AIS had a smoking history (44.5% vs. 40.1%) and cannabis use (2.4% vs. 1.6%).

Finally, we also found that the MS cases were younger, with a mean age of 62.89 years vs. 69.97 years, had a shorter stay of 4.91 days vs. 5.04 days, and a lower mean hospital charge ($67,201 vs. $71,186). During their stay, 1.9% of MS patients admitted with AIS died (vs. 3.7% in non-MS cases). After adjusting for multiple confounders, the adjusted odds ratio of death among MS patients with AIS compared to non-MS patients was 0.555 (95% confidence interval 0.405-0.760, p<0.05).
MS patients admitted with AIS have a lower mortality risk than non-MS cases. This can be related to the differences seen in age and multiple comorbidities.
Sailaja Sanikommu, MBBS (V.N.M Hopsital)
Dr. Sanikommu has nothing to disclose.
Shaheen Sombans, MBBS (Fernandez Foundation) Dr. Sombans has nothing to disclose.
Kamleshun Ramphul, MD Dr. Ramphul has nothing to disclose.
Renuka Verma, MD (KIRK KERKORIAN SCHOOL OF MEDICINE) Dr. Verma has nothing to disclose.
Yogeshwaree Ramphul, MD Dr. Ramphul has nothing to disclose.
Petras Jairam Das Lohana, MD,MBBS (Jacobi Medical Center) Dr. Jairam Das Lohana has nothing to disclose.
Indu Meena, MBBS Dr. Meena has nothing to disclose.
Komal Kumari, MBBS (Jacobi Medical Center) Dr. Kumari has nothing to disclose.
Stephanie Gonzalez Mejias, MD Dr. Gonzalez Mejias has nothing to disclose.
Nomesh Kumar, MD (Detroit Medical Center) Dr. Kumar has nothing to disclose.
Fnu Arti, MD,MBBS (Medstar Union Memorial Hospital) Dr. Arti has nothing to disclose.