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Abstract Details

The PD-Ballet Study: A World First Randomised Controlled, Single-blinded, Diversity-enabled Trial of Dance Therapy for Parkinson’s
Movement Disorders
P9 - Poster Session 9 (8:00 AM-9:00 AM)
3-002
To date, beneficial effects of multimodal exercise programmes on Parkinson’s disease (PD) have focused on motor symptoms and little attention has been paid to the potential effects of such programmes on the non-motor symptoms of PD, which are now universally known as one of the key drivers of quality of life and a key unmet need [1].  

To evaluate the effects of a ballet-based world first dance intervention on the key non-motor and motor symptoms of Parkinson’s disease using validated outcome measures. 

A randomised, single-blind, controlled, diversity-enabled trial of 77 people with Parkinson’s across all motor stages randomly allocated to either an intervention (n=53) or a control group (n=24). Primary outcome was a change in non-motor symptoms as measured by the Movement Disorders Society Non-Motor Scale (MDS-NMS). The intervention protocol consisted of 12 one-weekly dance sessions led by English National Ballet dancers, as part of the Wellcome Trust-funded SHAPER programme. Each session was followed by a ‘tea and biscuit’ social time. Control group followed standard clinical pathway and joined the ‘tea and biscuit’ to control for any positive effects of social interactions. All participants were assessed at baseline, immediately after completion of the intervention and 3-6 months later to explore any potential longitudinal effects. 

Immediate follow-up data were analysed. No significant differences between active and control groups were found at baseline. Between-group differences in MDS-NMS total scores were observed at immediate follow up (p=0.002). In addition, significant improvements  were observed in the Movement Disorders Society-Unified PD Rating Scale total score (p<0.001) as well as the King’s Parkinson Pain Scale total score (p=0.035) in the active group. 

Multimodal, programmed exercise interventions such as PD-Ballet can lead to an improvement of overall non-motor burden, pain and motor symptoms, including but not limited to activities of daily living.  

Authors/Disclosures
Aleksandra Podlewska, PhD (King's College London)
PRESENTER
Miss Podlewska has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Bial . The institution of Miss Podlewska has received research support from Wellcome Trust.
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Kallol R. Chaudhuri, MD, FRCP Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbvie, Acadia, GSK, Scion, Britannia , Lobsor. Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Abbvie, Britannia, Scion, Sunovion, UCB, . Dr. Chaudhuri has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbvie, Britannia, UCB, Zambon. Dr. Chaudhuri has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NPJ PD journal. The institution of Dr. Chaudhuri has received research support from Britania Pharmaceuticals, AbbVie, UCB, GKC, Bial, Aacdemic grants: EU, IMI EU, Horizon 2020, Parkinson's UK, NIHR, PDNMG, EU (Horizon 2020), Kirby Laing Foundation, NPF, MRC, Wellcome Trust.