2023 Annual Meeting | S22 - Autoimmune Neurology: Autoimmune Encephalitis and Other Antibody-associated Syndromes

Date Monday 04/24/23

Time 03:30 PM - 05:30 PM EST Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program will be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Moderator(s) Anastasia Zekeridou, MD, PhD, FAAN, Prashanth S. Ramachandran, Jr., MBBS

Topic(s) Autoimmune Neurology

Learning Objectives A group of abstracts covering a similar topic presented in an oral format. Presentations are eight minutes in length with four minutes for question and answer with the author.

CME Available 2.00 CME credits

Recommended Audience Fellow, Resident, General Neurologist, Specialist Neurologist, Non-neurologist, Advanced Practice Provider, Neurohospitalist, Medical Student

Teaching Styles Didactic

Event Timeline
03:30 PM - 03:42 PM EST	Speaker	2023 Alliance Award Founders: This award is designed to encourage clinical and translational research in neuroscience by physicians in clinical neurology training programs. Alexander Sandweiss, MD, PhD
03:42 PM - 03:54 PM EST	Speaker	2023 Alliance Award S. Weir Mitchell: This award is designed to encourage basic research in neuroscience by physicians in clinical neurology training programs. John Pluvinage, MD, PhD
03:54 PM - 04:06 PM EST	Abstract	003 - MRI Features and their Association with Outcomes in Children with Anti-NMDA Receptor Encephalitis Coral M. Stredny, MD
04:06 PM - 04:18 PM EST	Abstract	004 - Frontal cognitive-behavioural deficits in patients with anti-leucine-rich glioma-inactivated protein 1 antibody encephalitis Sydney Lee, MD
04:18 PM - 04:30 PM EST	Abstract	005 - Monoclonal Humanized One-Armed Antibody Blocking Therapy for Anti-NMDAR Encephalitis Mitsuyuki Matsumoto, PhD
04:30 PM - 04:42 PM EST	Abstract	006 - Clinical characterisation of patients in the post-acute stage of anti-NMDA receptor encephalitis: a prospective cohort study and comparison with patients with schizophrenia spectrum disorders Mar Guasp, MD
04:42 PM - 04:54 PM EST	Abstract	007 - Cognitive Impairment is Associated with Longitudinal Disability in LGI-1-IgG Encephalitis Albert Aboseif, DO
04:54 PM - 05:06 PM EST	Abstract	008 - Animal model of HSV-induced-NMDAR Autoimmune Encephalitis affects predominantly female mice Alexander Sandweiss, MD, PhD
05:06 PM - 05:18 PM EST	Abstract	009 - Long Term Outcomes in Patients with Anti-DPPX Autoimmunity Lisette Dominguez, DO
05:18 PM - 05:30 PM EST	Abstract	010 - Frequency of anti-IgLON5 disease in patients who meet the clinical diagnostic criteria for progressive supranuclear palsy/corticobasal syndrome Yoya Ono

Faculty Disclosures
Gregory S. Day, MD, MSc, FAAN	Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Parabon Nanolabs. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Arialys Therapeutics. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for DynaMed (EBSCO Health). Dr. Day has stock in ANI Pharmaceuticals. The institution of Dr. Day has received research support from National Institutes of Health / NIA. The institution of Dr. Day has received research support from Chan Zuckerberg Initiative. The institution of Dr. Day has received research support from Alzheimer's Association. The institution of Dr. Day has received research support from National Institutes of Health / NINDS. The institution of Dr. Day has received research support from Amgen Pharmaceuticals. The institution of Dr. Day has received research support from AVID Radiopharmaceuticals. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Presenter at Annual Meeting (CME) with American Academy of Neurology. Dr. Day has received personal compensation in the range of $500-$4,999 for serving as a Content Development (CME) with PeerView, Inc. Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Content Development (CME) with Continuing Education, Inc. Dr. Day has received personal compensation in the range of $5,000-$9,999 for serving as a Content Development (CME) with Ionis Pharmaceuticals. Dr. Day has a non-compensated relationship as a Clinical Director with AntiNMDA Receptor Encephalitis Foundation that is relevant to AAN interests or activities.
Coral M. Stredny, MD	Dr. Stredny has stock in Proctor and Gamble. The institution of Dr. Stredny has received research support from Pediatric Epilepsy Research Foundation.
Mar Guasp, MD	Dr. Guasp has nothing to disclose.
James N. Brenton, MD	Dr. Brenton has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for I-ACT on a Novartis sponsored project. The institution of Dr. Brenton has received research support from NIH/NINDS. The institution of Dr. Brenton has received research support from Autoimmune Encephalitis Alliance. Dr. Brenton has received publishing royalties from a publication relating to health care. Dr. Brenton has received personal compensation in the range of $500-$4,999 for serving as a Grant Reviewer with Department of Defense. Dr. Brenton has received personal compensation in the range of $0-$499 for serving as a Grant Reviewer with NIH. Dr. Brenton has received personal compensation in the range of $0-$499 for serving as a Grant Reviewer with FDA.
Jonathan Santoro, MD	Dr. Santoro has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for UCB. Dr. Santoro has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Cycle Pharma.
Albert Aboseif, DO	Dr. Aboseif has a non-compensated relationship as a AAN Autoimmune Neurology Section -- Education Workgroup with AAN that is relevant to AAN interests or activities.
Atsuo Kanno	No disclosure on file
Alexandra Muccilli, MD	Dr. Muccilli has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Muccilli has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Muccilli has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for EMD Serono. Dr. Muccilli has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion.
Eugenia Martinez-Hernandez, MD	The institution of Dr. Martinez-Hernandez has received research support from Instituto de Salud Carlos III. Dr. Martinez-Hernandez has received personal compensation in the range of $0-$499 for serving as a travel and speaking honoraria with Biogen. Dr. Martinez-Hernandez has received personal compensation in the range of $0-$499 for serving as a travel honoraria with UCB.
Jennifer H. Yang, MD	The institution of Dr. Yang has received research support from Pediatric Epilepsy Research Foundation. The institution of Dr. Yang has received research support from NIH.
Alexander Sandweiss, MD, PhD	Dr. Sandweiss has nothing to disclose.
Amy Kunchok, MBBS	Dr. Kunchok has received personal compensation in the range of $0-$499 for serving as a Consultant for EMD Serono. Dr. Kunchok has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon therapeutics . Dr. Kunchok has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion. Dr. Kunchok has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Neurology.
Kristy Murray	No disclosure on file
Alfonso S. Lopez, MD	Dr. Lopez has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon. Dr. Lopez has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech .
Claude Steriade, MD	The institution of Dr. Steriade has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for The Epilepsy Study Consortium. Dr. Steriade has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Dynamed. Dr. Steriade has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for DOJ. The institution of Dr. Steriade has received research support from NIH. Dr. Steriade has received personal compensation in the range of $500-$4,999 for serving as a Consultant with Epitel. Dr. Steriade has received personal compensation in the range of $500-$4,999 for serving as a Consultant with Jazz Pharmaceuticals.
Andrew McKeon, MD	The institution of Dr. McKeon has received research support from National Institutes of Health. Dr. McKeon has received intellectual property interests from a discovery or technology relating to health care. Dr. McKeon has received intellectual property interests from a discovery or technology relating to health care. Dr. McKeon has received publishing royalties from a publication relating to health care.
	No disclosure on file
Helena Arino, MD, PhD	Ms. Arino has nothing to disclose.
Raquel Sanchez Del Valle Diaz, MD	No disclosure on file
Vineet Punia, MD	Dr. Punia has nothing to disclose.
Joan Santamaria, MD	Joan Santamaria, MD has nothing to disclose.
Yadi Li	No disclosure on file
Sydney Lee, MD	Dr. Lee has nothing to disclose.
Rachel Galioto	Rachel Galioto has nothing to disclose.
Ryan Kammeyer, MD	Dr. Kammeyer has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Ogborn-Mihm Trial Lawyers. The institution of Dr. Kammeyer has received research support from Rocky Mountain Multiple Sclerosis Center.
Anusha Yeshokumar, MD	Dr. Yeshokumar has nothing to disclose.
Karla Robles Lopez	No disclosure on file
Kazuko Hasegawa, MD	Dr. Hasegawa has nothing to disclose.
Josep O. Dalmau, MD, PhD, FAAN	Dr. Dalmau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Astellas Research Institute of America. Dr. Dalmau has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen Research & Development . Dr. Dalmau has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for American Academy of Neurology. An immediate family member of Dr. Dalmau has received personal compensation in the range of $5,000-$9,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer Nature. The institution of Dr. Dalmau has received research support from Sage Therapeutics. The institution of Dr. Dalmau has received research support from Edmond J.Safra Foundation . The institution of Dr. Dalmau has received research support from La Caixa Foundation. The institution of Dr. Dalmau has received research support from Spanish Ministry of Health (ISCIII). The institution of Dr. Dalmau has received research support from Euroimmun, Inc. Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Dalmau has received intellectual property interests from a discovery or technology relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care. Dr. Dalmau has received publishing royalties from a publication relating to health care.
Amaia Muñoz-Lopetegi	Ms. Muñoz-Lopetegi has nothing to disclose.
Masashi Maeda	No disclosure on file
Yike Jiang	No disclosure on file
Justin Abbatemarco, MD	Dr. Abbatemarco has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for EMD Serono. Dr. Abbatemarco has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Horizon. Dr. Abbatemarco has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech . Dr. Abbatemarco has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for TG Therapeutics, Inc.. The institution of Dr. Abbatemarco has received research support from Horizon.
Grace Gombolay, MD	Dr. Gombolay has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Pediatric Neurology. An immediate family member of Dr. Gombolay has received personal compensation in the range of $500-$4,999 for serving as an Expert Witness for Washington Injury Lawyers. The institution of Dr. Gombolay has received research support from CDC. The institution of Dr. Gombolay has received research support from NIH.
Takayoshi Shimohata, MD, FAAN	Dr. Shimohata has nothing to disclose.
Ronald C. Ramos, MD	Dr. Ramos has nothing to disclose.
Domingo Escudero, MD	Dr. Escudero has nothing to disclose.
Morgan Morris	No disclosure on file
Lisette Dominguez, DO	Dr. Dominguez has nothing to disclose.
Ilana L. Kahn, MD	Dr. Kahn has nothing to disclose.
Sarah Lapointe, MD	Dr. Lapointe has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alexion.
Yoya Ono	Yoya Ono has nothing to disclose.
Takeshi Ikeuchi, MD	Dr. Ikeuchi has nothing to disclose.
Manikum Moodley, MD	Dr. Moodley has nothing to disclose.
Julien Hebert, MD	Dr. Hebert has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Paladin Labs.
Mark Gorman, MD	The institution of Dr. Gorman has received research support from Pfizer. The institution of Dr. Gorman has received research support from Roche / Genetech .
Masato Kanazawa, MD, FAAN	Dr. Kanazawa has nothing to disclose.
Satoshi Kubo	No disclosure on file
Roghiye Kazimi	Roghiye Kazimi has nothing to disclose.
Nobuaki Yoshikura, MD, PhD	Dr. Yoshikura has nothing to disclose.
Seth A. Climans, MD	Dr. Climans has nothing to disclose.
Catherine E. Otten, MD	The institution of Dr. Otten has received research support from CDC.
Brittany Lapin	No disclosure on file
Alexander D. Rae-Grant, MD, FAAN	Dr. Rae-Grant has received publishing royalties from a publication relating to health care. Dr. Rae-Grant has received publishing royalties from a publication relating to health care.
Shanni Yamaki	Shanni Yamaki has received personal compensation for serving as an employee of Arialys Therapeutics Inc. .
Ritsuko Hanajima, MD, PhD	No disclosure on file
Jay Lichter, PhD	Dr. Lichter has received personal compensation in the range of $50,000-$99,999 for serving as an officer or member of the Board of Directors for Janux.
Sara Llufriu	Sara Llufriu has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Sara Llufriu has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis. Sara Llufriu has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Merci. Sara Llufriu has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbot. Sara Llufriu has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Sanofi.
Mitsuya Morita, MD, PhD	Dr. Morita has nothing to disclose.
Thais Armangue, MD	Dr. Armangue has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. The institution of Dr. Armangue has received research support from ISCIII(Spanish institute of health) -PI21/00316, Marato TV3, La Caixa Research Foundadion, Pablove Foundation (689368), Torrons Vicens Foundation (PFNR0144), 2021 Invest AEP.
Andrew Christiana, MD	Dr. Christiana has nothing to disclose.
Hisanori Kowa, MD, PhD	Dr. Kowa has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for DAIICHI SANKYO COMPANY, LIMITED. Dr. Kowa has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eli Lilly Japan K.K.. Dr. Kowa has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Otsuka Pharmaceutical Co., Ltd.. Dr. Kowa has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amgen Inc.. Dr. Kowa has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Takeda Pharmaceutical Company Limited.. Dr. Kowa has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Kyowa Kirin Co., Ltd.. Dr. Kowa has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Chugai Pharmaceutical Co., Ltd.. Dr. Kowa has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for ONO PHARMACEUTICAL CO., LTD..
Alexandra B. Kornbluh, MD	Dr. Kornbluh has nothing to disclose.
Leigh N. Sepeta, PhD	Dr. Sepeta has received personal compensation in the range of $500,000-$999,999 for serving as a Grant PI with Nih. Dr. Sepeta has a non-compensated relationship as a Special volunteer with Nih that is relevant to AAN interests or activities.
Akio Kimura, MD	Dr. Kimura has nothing to disclose.
Duriel I. Hardy, MD	Dr. Hardy has nothing to disclose.
Mathew Mitchell	Mr. Mitchell has received personal compensation for serving as an employee of Arialys Therapeutics.
NgocHanh H. Vu, MD	Dr. Vu has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Syneos Health.
Mitsuyuki Matsumoto, PhD	Dr. Matsumoto has received personal compensation for serving as an employee of Arialys Therapeutics, Inc.. Dr. Matsumoto has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for Arialys Therapeutics, Inc.. Dr. Matsumoto has stock in Arialys Therapeutics, Inc.. Dr. Matsumoto has received intellectual property interests from a discovery or technology relating to health care.
Moein Amin, MD	Dr. Amin has nothing to disclose.
Ikuko Aiba	Ikuko Aiba has nothing to disclose.
Akira Takekoshi	Akira Takekoshi has nothing to disclose.
David F. Tang-Wai, MD, FRCPC	Dr. Tang-Wai has nothing to disclose.
John Pluvinage, MD, PhD	Dr. Pluvinage has received research support from National Institute on Aging.
Anastasia Zekeridou, MD, PhD, FAAN	The institution of Dr. Zekeridou has received research support from Roche/Genentech. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care. Dr. Zekeridou has received intellectual property interests from a discovery or technology relating to health care.
Prashanth S. Ramachandran, Jr., MBBS	Dr. Ramachandran has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Biogen. Dr. Ramachandran has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Merk.