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2024 Annual Meeting | N5 - Neuroscience in the Clinic: Exploring the Gut-brain Axis

Wednesday 04/17/24
03:30 PM - 05:30 PM MDT Add To Calendar
Colorado Convention Center | Bluebird 1B
This program will be presented both in-person and online
This program will be available in the meeting's On Demand product.
Neuroscience in the Clinic Session
Roneil Malkani, MD, Howard L. Weiner, MD
General Neurology, Movement Disorders, Epilepsy/Clinical Neurophysiology (EEG), Epilepsy/Clinical Neurophysiology (EEG), Movement Disorders
Participants should be able to describe the relationships between the gut microbiome on the pathophysiology and function in neurologic diseases, including multiple sclerosis, autism, and neurodegenerative disorders such as Alzheimer’s disease and Parkinson's disease.
2.00 CME credits
Patient Care & Procedural Skills, Medical Knowledge, Practice-based Learning and Improvement
Intermediate
Brain Health
Fellow, Resident, General Neurologist, Specialist Neurologist, Non-neurologist, Advanced Practice Provider, Medical Student
Case-based, Didactic

Program Materials Program Evaluations

Event Timeline
03:30 PM - 03:35 PM MDT Introduction Introduction
Roneil Malkani, MD
03:35 PM - 03:45 PM MDT Speaker Case Presentation
Juan Ramon Deliz Gonzalez, MD
03:45 PM - 04:10 PM MDT Speaker Microbiome Immune Interactions in Multiple Sclerosis and Alzheimer's Disease
Laura M. Cox, PhD
04:10 PM - 04:35 PM MDT Speaker Contributions of the Gut Microbiome to Parkinson's Disease Pathologies
Tim Sampson, PhD
04:35 PM - 04:45 PM MDT Abstract 001 - Effects of a four-strain probiotic on inflammatory markers in Parkinson's disease: a multicentre randomised controlled trial (the SymPD study)
Valentina Leta, MD
04:45 PM - 05:10 PM MDT Speaker Improving the Microbiome to Manage Autism Spectrum Disorder Symptoms
Rosa Krajmalnik-Brown, PhD
05:10 PM - 05:20 PM MDT Abstract 002 - Shotgun Metagenomic Analysis to Study the Role of Gut Dysbiosis in Drug-Resistant Epilepsy
William C.Y. Leung, MBBS, MRCP, FHKAM
05:20 PM - 05:25 PM MDT Speaker Case Follow-up
05:25 PM - 05:30 PM MDT Q&A Wrap-up and Q&A
Roneil Malkani, MD, Howard L. Weiner, MD, Laura M. Cox, PhD, Rosa Krajmalnik-Brown, PhD, Tim Sampson, PhD
Faculty Disclosures
Roneil Malkani, MD The institution of Dr. Malkani has received research support from NIH. The institution of Dr. Malkani has received research support from Northwestern University. Dr. Malkani has received personal compensation in the range of $500-$4,999 for serving as a Author with American Academy of Neurology. Dr. Malkani has received personal compensation in the range of $500-$4,999 for serving as a Reviewer with Weston Family Foundation. Dr. Malkani has a non-compensated relationship as a Committee Member with American Academy of Sleep Medicine that is relevant to AAN interests or activities. Dr. Malkani has a non-compensated relationship as a Board Member with Illinois Sleep Society that is relevant to AAN interests or activities. Dr. Malkani has a non-compensated relationship as a Review editor on editorial board with Frontiers that is relevant to AAN interests or activities.
Howard L. Weiner, MD Dr. Weiner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Genentech. Dr. Weiner has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medday Pharmaceuticals. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for vTv Therapeutics. Dr. Weiner has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Tiziana Life Sciences. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for vTv Therapeutics. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Medday Pharmaceuticals. Dr. Weiner has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for vTv Therapeutics. Dr. Weiner has stock in vTv Therapeutics. The institution of Dr. Weiner has received research support from National Institute of Health. The institution of Dr. Weiner has received research support from National MS Society. The institution of Dr. Weiner has received research support from Genzyme Corp. The institution of Dr. Weiner has received research support from Genentech, Inc. . The institution of Dr. Weiner has received research support from Verily Life Sciences LLC. The institution of Dr. Weiner has received research support from EMD Serono, Inc..
Laura M. Cox, PhD Dr. Cox has received personal compensation for serving as an employee of Anaerobe Systems. The institution of Dr. Cox has received research support from Infectious Disease Society. The institution of Dr. Cox has received research support from BrightFocus Foundation. The institution of Dr. Cox has received research support from National Institutes of Health. The institution of Dr. Cox has received research support from Department of Defense. Dr. Cox has received intellectual property interests from a discovery or technology relating to health care.
Rosa Krajmalnik-Brown, PhD Rosa Krajmalnik-Brown, PhD has received personal compensation in the range of $0-$499 for serving on a Scientific Advisory or Data Safety Monitoring board for Finch Therapeutics. Rosa Krajmalnik-Brown, PhD has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Spinger Nature. Rosa Krajmalnik-Brown, PhD has stock in GBAT. Rosa Krajmalnik-Brown, PhD has received intellectual property interests from a discovery or technology relating to health care.
Tim Sampson, PhD The institution of Dr. Sampson has received research support from NIH; NIEHS. The institution of Dr. Sampson has received research support from Aligning Science Against Parkinson's. The institution of Dr. Sampson has received research support from Parkinson's Foundatiion.
William C.Y. Leung, MBBS, MRCP, FHKAM Dr. Leung has nothing to disclose.
Xueyan HU Miss HU has nothing to disclose.
Joshua Ho, PhD The institution of Dr. Ho has received research support from Innovation and Technology Commission of Hong Kong. The institution of Dr. Ho has received research support from Shenzhen Hong Kong Macau Technology Programme.
Holy MH Chan, MBBS Miss Chan has nothing to disclose.
Hui Ning Florinda Chu, MBBS Dr. Chu has nothing to disclose.
Cheuk Nam Rachel Lo Miss Lo has nothing to disclose.
Gary KK Lau, MBBS Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Amgen. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Daiichi Sankyo. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amgen. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Boehringer Ingelheim. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Daiichi Sankyo. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Pfizer. Dr. Lau has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Eisai. The institution of Dr. Lau has received research support from Croucher Foundation. The institution of Dr. Lau has received research support from Research Fund Secretariat of the Food and Health Bureau, Hong Kong. The institution of Dr. Lau has received research support from Innovation and Technology Bureau, Hong Kong. The institution of Dr. Lau has received research support from Research Grants Council, Hong Kong. Dr. Lau has received publishing royalties from a publication relating to health care.
Wui Hang Ho, MBBS Dr. Ho has nothing to disclose.
Valentina Leta, MD The institution of Valentina Leta, MD has received research support from Parkinson's UK. The institution of Valentina Leta, MD has received research support from NIHR BRC. The institution of Valentina Leta, MD has received research support from Symprove ltd. Valentina Leta, MD has received personal compensation in the range of $500-$4,999 for serving as a Speaker, and member of advisory board with Bial. Valentina Leta, MD has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Merz. Valentina Leta, MD has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Abbvie. Valentina Leta, MD has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Britannia.
Gargi Mandal Miss Mandal has nothing to disclose.
Pavlos Zinzalias Mr. Zinzalias has nothing to disclose.
Juliet Staunton Ms. Staunton has nothing to disclose.
Lucia Batzu, MD Dr. Batzu has nothing to disclose.
Dhaval Trivedi The institution of Dhaval Trivedi has received research support from Symprove ltd .
Kristina Rosqvist, PhD Dr. Rosqvist has nothing to disclose.
Jonathan Timpka, MD,PhD Dr. Timpka has received personal compensation in the range of $0-$499 for serving as a Consultant for TransPerfect. The institution of Dr. Timpka has received research support from Swedish Parkinson Foundation. Dr. Timpka has received personal compensation in the range of $0-$499 for serving as a Expert with Swedish National Board of Health and Welfare.
Trinette Van Vliet, PhD Mrs. Van Vliet has nothing to disclose.
Aleksandra Podlewska, PhD Miss Podlewska has received personal compensation in the range of $0-$499 for serving on a Speakers Bureau for Bial . The institution of Miss Podlewska has received research support from Wellcome Trust.
Miriam Parry Ms. Parry has nothing to disclose.
Daniel van Wamelen No disclosure on file
Alexandra Rizos, Other An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for UCB. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for GKC. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bial. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Cynapsus. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lobsor. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Stada. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Zambon. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Profile Pharma. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Synovion. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Theravance. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Scion. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Britannia. Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Britannia. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Britannia. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for UCB. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Zambon. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Novartis. An immediate family member of Mrs. Rizos has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Boehringer Ingelheim. An immediate family member of Mrs. Rizos has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Nature Parkinson's Journal. The institution of an immediate family member of Mrs. Rizos has received research support from EU. The institution of an immediate family member of Mrs. Rizos has received research support from Parkinson's UK. The institution of an immediate family member of Mrs. Rizos has received research support from Parkinson's Foundation. The institution of an immediate family member of Mrs. Rizos has received research support from Wellcome trust. The institution of an immediate family member of Mrs. Rizos has received research support from MRC. An immediate family member of Mrs. Rizos has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Mrs. Rizos has received publishing royalties from a publication relating to health care. An immediate family member of Mrs. Rizos has received publishing royalties from a publication relating to health care.
Guy Chung-Faye, PhD,MBBS Dr. Chung-Faye has nothing to disclose.
Per Odin Per Odin has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AbbVie. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AbbVie. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Lobsor. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AbbVie. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Britannia. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for UCB. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Nordic Infucare. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Zambon. Per Odin has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Bial. The institution of Per Odin has received research support from AbbVie. The institution of Per Odin has received research support from Parkinsonfonden. The institution of Per Odin has received research support from Swedish Research Council. The institution of Per Odin has received research support from Region Skåne. Per Odin has received publishing royalties from a publication relating to health care.
Carmine Pariante, MD,PhD Prof. Pariante has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for 2021 Lundbeck (Italia) conference inflammation 1,500 euros 2021 Lundbeck (Italia) conference inflammation 2,000 euros . The institution of Prof. Pariante has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Editor Brain Behavior and Immunity (BBI), BBI Health and BBI Integrative. The institution of Prof. Pariante has received research support from 2022 Compass trial on PTSD £89,020.
Alessandra Borsini, PhD Dr. Borsini has nothing to disclose.
Kallol Ray Chaudhuri, MD,FRCP Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbvie, Acadia, GSK, Scion, Britannia , Lobsor. Dr. Chaudhuri has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Abbvie, Britannia, Scion, Sunovion, UCB, . Dr. Chaudhuri has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Abbvie, Britannia, UCB, Zambon. Dr. Chaudhuri has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for NPJ PD journal. The institution of Dr. Chaudhuri has received research support from Britania Pharmaceuticals, AbbVie, UCB, GKC, Bial, Aacdemic grants: EU, IMI EU, Horizon 2020, Parkinson's UK, NIHR, PDNMG, EU (Horizon 2020), Kirby Laing Foundation, NPF, MRC, Wellcome Trust.
Juan Ramon Deliz Gonzalez, MD Dr. Deliz Gonzalez has nothing to disclose.