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2024 Annual Meeting | S26 - Movement Disorders: Basic Science

Tuesday 04/16/24
03:30 PM - 05:30 PM MDT Add To Calendar
Colorado Convention Center | Mile High 4EF
This program will be presented both in-person and online
This program will be available in the meeting's On Demand product.
Scientific Platform Session
Movement Disorders
 A group of abstracts covering a similar topic will be presented in an eight-minute oral format followed by four minutes for question and answer with the author. 
2.00 CME credits

Program Materials Program Evaluations

Event Timeline
03:30 PM - 03:54 PM MDT Speaker 2024 Movement Disorders Research Award: This award recognizes an individual for outstanding work in the field of Parkinson's disease or other movement disorders for either a single outstanding contribution or for lifetime achievement.
David Rubinsztein, MBChB, PhD
03:54 PM - 04:06 PM MDT Abstract 003 - Relationships Between Regional Burden of Tau Neuropathology and Age at Death and Disease Duration in Patients with Progressive Supranuclear Palsy
Negin Badihian, MD
04:06 PM - 04:18 PM MDT Abstract 004 - A Novel Diagnostic Method for Detection and Quantitation of Cutaneous Phosphorylated Alpha-synuclein
Christopher H. Gibbons, MD, FAAN
04:18 PM - 04:30 PM MDT Abstract 005 - a-Synuclein Aggregation Differentiates Parkinson’s Disease and Multiple System Atrophy in GI Tissue
Tritia Reina Yamasaki, MD, PhD, FAAN
04:30 PM - 04:42 PM MDT Abstract 006 - Alpha-Synuclein Strains in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies
George Kannarkat
04:42 PM - 04:54 PM MDT Abstract 007 - Investigating the Indirect Interaction Between Vps35 and a-synuclein in Parkinson’s Disease
Michele Persico, MD
04:54 PM - 05:06 PM MDT Abstract 008 - Blood Mitochondrial DNA Copy Number Is Associated with Motor Symptoms and Dementia in Parkinson’s Disease
Sun Ju Chung, MD, PhD, FAAN
05:06 PM - 05:18 PM MDT Abstract 009 - Intraputaminal AAV-CAv1.3-shRNA Averts Levodopa-induced Dyskinesias and Ameliorates Long-standing Parkinsonian Motor Deficits in Aged Parkinsonian Macaques
Margaret Caulfield, PhD
05:18 PM - 05:30 PM MDT Abstract 010 - Striatal Cholinergic Agonist Infusion Induces a Dystonic Phenotype in Non-human Primate
Edouard Courtin, MBBS
Faculty Disclosures
Ihtsham Haq, MD, FAAN The institution of Dr. Haq has received research support from NINDS. The institution of Dr. Haq has received research support from the Parkinson's Foundation. The institution of Dr. Haq has received research support from NIMH. Dr. Haq has a non-compensated relationship as a consultant with Medtronics that is relevant to AAN interests or activities. Dr. Haq has a non-compensated relationship as a consultant with Boston Scientific that is relevant to AAN interests or activities. Dr. Haq has a non-compensated relationship as a consultant with Abbott that is relevant to AAN interests or activities.
Claire Henchcliffe, MD, PhD, FAAN Dr. Henchcliffe has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Bayer. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AskBio. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Consultant for Certara. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Meira GTx. Dr. Henchcliffe has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for ProJenX. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Canary Global Inc . Dr. Henchcliffe has stock in Axent Biosciences Inc. The institution of Dr. Henchcliffe has received research support from Weston Brain Institute. The institution of Dr. Henchcliffe has received research support from Blue Rock Therapeutics. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker with Parkinson Study Group. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker with UCLA. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker travel with World Congress of Neurology. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Speaker travel with IAPRD. Dr. Henchcliffe has received personal compensation in the range of $0-$499 for serving as a Speaker travel with ASGCT. Dr. Henchcliffe has received personal compensation in the range of $500-$4,999 for serving as a Speaker/Course director with AAN.
David Rubinsztein, MBChB, PhD David Rubinsztein, MBChB, PhD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Aladdin healthcare. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Nido Biosciences. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Mindrank AI. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Drishti Discoveries. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Retro Biosciences. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for PAQ Therapeutics. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Cell Death and Differentiation - journal. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Ageing and Neurodegenerative Diseases. The institution of David Rubinsztein, MBChB, PhD has received research support from National Institute for Health Research - Biomedical Research Centre for Addenbrooke's Hospital . The institution of David Rubinsztein, MBChB, PhD has received research support from UK Dementia Research Institute Professorship programme (funded by Medical Research Council/Alzheimer's Society/Alzheimer's Research UK). The institution of David Rubinsztein, MBChB, PhD has received research support from Anonymous Donor. Rubinsztein laboratory component of The Cambridge Centre for Parkinson-Plus. The institution of David Rubinsztein, MBChB, PhD has received research support from The Roger de Spoelberch Prize. Project component of award: . The institution of David Rubinsztein, MBChB, PhD has received research support from Servier. The institution of David Rubinsztein, MBChB, PhD has received research support from Alzheimer's Research UK. The institution of David Rubinsztein, MBChB, PhD has received research support from Merck Sharp and Dohme. The institution of David Rubinsztein, MBChB, PhD has received research support from EU Horizon 2020 . The institution of David Rubinsztein, MBChB, PhD has received research support from Alzheimer's Research UK Cambridge Drug Discovery Institute. The institution of David Rubinsztein, MBChB, PhD has received research support from Rosetrees Trust and The John Black Charitable Foundation. The institution of David Rubinsztein, MBChB, PhD has received research support from UK Dementia Research Institute. The institution of David Rubinsztein, MBChB, PhD has received research support from Tau Consortium. The institution of David Rubinsztein, MBChB, PhD has received research support from AstraZeneca. The institution of David Rubinsztein, MBChB, PhD has received research support from MSD Action Foundation. The institution of David Rubinsztein, MBChB, PhD has received research support from Medical Research Charities Group/Health Research Board. The institution of David Rubinsztein, MBChB, PhD has received research support from Alzeimer's Research UK. The institution of David Rubinsztein, MBChB, PhD has received research support from Great Ormond Street Hospital Children's Charity. The institution of David Rubinsztein, MBChB, PhD has received research support from Parkinson's UK. The institution of David Rubinsztein, MBChB, PhD has received research support from PSMC5 Foundation. The institution of David Rubinsztein, MBChB, PhD has received research support from Wellcome Leap. The institution of David Rubinsztein, MBChB, PhD has received research support from Medical Research Council. The institution of David Rubinsztein, MBChB, PhD has received research support from US National Academy of Medicine. The institution of David Rubinsztein, MBChB, PhD has received research support from Medical Resarch Council. David Rubinsztein, MBChB, PhD has received intellectual property interests from a discovery or technology relating to health care. David Rubinsztein, MBChB, PhD has received personal compensation in the range of $500-$4,999 for serving as a seminar speaker with Various Universities internationally.
Tadanori Hamano No disclosure on file
Michele Persico, MD Dr. Persico has nothing to disclose.
Tracy-Shi Zhang Fang, PhD Dr. ZHANG has nothing to disclose.
Simona Eleuteri, PhD Dr. Eleuteri has nothing to disclose.
David K. Simon, MD, PhD Dr. Simon has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Bial Biotech. An immediate family member of Dr. Simon has stock in Biogen. The institution of Dr. Simon has received research support from Weston Brain Institute. The institution of Dr. Simon has received research support from NIH. The institution of Dr. Simon has received research support from Neuraly. Dr. Simon has received personal compensation in the range of $5,000-$9,999 for serving as a Steering Committee Member: SPARK clinical study with Biogen. Dr. Simon has received personal compensation in the range of $500-$4,999 for serving as a Steering Committee Member: NILO-PD clinical study with Michael J Fox Foundation.
Carly Laura Tucci Miss Tucci has nothing to disclose.
Man Mohan Mehndiratta, MD, MBBS, FAAN Dr. Mehndiratta has nothing to disclose.
Margaret Caulfield, PhD The institution of Dr. Caulfield has received research support from Department of Defense.
Kathy Steece-Collier, PhD Prof. Steece-Collier has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for RegenxBio. Prof. Steece-Collier has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Pontifax. The institution of Prof. Steece-Collier has received research support from NIH/NINDS.
Molly Vander Werp Ms. Vander Werp has nothing to disclose.
Scott Muller Mr. Muller has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for RYNE Biotechnology.
Jennifer Stancati, Other Ms. Stancati has nothing to disclose.
Timothy Collier The institution of Timothy Collier has received research support from NIH.
Fredric Manfredsson, PhD Prof. Manfredsson has received personal compensation for serving as an employee of Seelos Therapeutics . Prof. Manfredsson has stock in NVector. Prof. Manfredsson has stock in Neuralina. Prof. Manfredsson has stock in Cavgene theraputics. Prof. Manfredsson has received intellectual property interests from a discovery or technology relating to health care. Prof. Manfredsson has received intellectual property interests from a discovery or technology relating to health care.
Yaping Chu, MD Mr. Chu has nothing to disclose.
Ivette Sandoval, PhD An immediate family member of Dr. Sandoval has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for SEELOS therapeutics. Dr. Sandoval has stock in nVector. An immediate family member of Dr. Sandoval has stock in nVector. An immediate family member of Dr. Sandoval has stock in CavGene. An immediate family member of Dr. Sandoval has stock in Neuralina. Dr. Sandoval has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Sandoval has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Sandoval has received intellectual property interests from a discovery or technology relating to health care. An immediate family member of Dr. Sandoval has received intellectual property interests from a discovery or technology relating to health care.
Jeffrey Kordower Dr. Kordower has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Seelos Inc. Dr. Kordower has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant for Abbvie Inc. Dr. Kordower has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Inhibikase Inc. Dr. Kordower has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Biogen. Dr. Kordower has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Renovacor/Rocket Pharm. Dr. Kordower has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Kirkland and Ellis Attorney's at Law. Dr. Kordower has stock in Inhibikase Inc. The institution of Dr. Kordower has received research support from Michael J. Fox Foundation. The institution of Dr. Kordower has received research support from Michael J. Fox Foundation. The institution of Dr. Kordower has received research support from Michael J. Fox Foundation. The institution of Dr. Kordower has received research support from Aligning Science Against Parkinson's (ASAP). The institution of Dr. Kordower has received research support from Biogen. The institution of Dr. Kordower has received research support from Abbvie. The institution of Dr. Kordower has received research support from Abbvie.
Werner J. Becker, MD Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for AbbVie. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Lundbeck. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eli Lilly. Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Novartis. Dr. Becker has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Teva. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving as a Consultant for McKesson. Dr. Becker has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for University of Calgary.
Sun Ju Chung, MD, PhD, FAAN Dr. Chung has nothing to disclose.
Ji-Hye Oh, PhD Ms. Oh has nothing to disclose.
Sungyang Jo, MD Dr. Jo has nothing to disclose.
Sangjin Lee, MD Dr. Lee has nothing to disclose.
Jihyun Lee, MD Dr. Lee has nothing to disclose.
Chang Ohk Sung, MD, PhD Prof. SUNG has nothing to disclose.
Daniela Berdnik No disclosure on file
Christopher H. Gibbons, MD, FAAN Dr. Gibbons has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Autonomic Neuroscience. Dr. Gibbons has stock in CND Life Sciences. Dr. Gibbons has received publishing royalties from a publication relating to health care. Dr. Gibbons has received personal compensation in the range of $5,000-$9,999 for serving as a Expert Advisor with Department of Justice.
Bailey Christopher Bellaire Mr. Bellaire has received personal compensation for serving as an employee of CND Life Sciences.
Todd D. Levine, MD Dr. Levine has received personal compensation for serving as an employee of CND life sciences . Dr. Levine has received personal compensation in the range of $100,000-$499,999 for serving as a Consultant for Nufactor. Dr. Levine has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Grifols. Dr. Levine has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for PNA. Dr. Levine has stock in CND Life Sciences. Dr. Levine has stock in Corinthian reference lab.
Roy L. Freeman, MD Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Regenacy. Dr. Freeman has received personal compensation in the range of $100,000-$499,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Neurobo. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Vertex. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eli-Lilly. Dr. Freeman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Theravance. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Inhibikase. Dr. Freeman has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Elsevier. Dr. Freeman has stock in Neurobo. Dr. Freeman has stock in Cutaneous NeuroDiagnostics. The institution of Dr. Freeman has received research support from NIH. The institution of Dr. Freeman has received research support from Theravance. The institution of Dr. Freeman has received research support from Biohaven. The institution of Dr. Freeman has received research support from Lundbeck.
Tony Wyss-Coray No disclosure on file
Edouard Courtin, MBBS Dr. Courtin has nothing to disclose.
Pierre Burbaud, Sr. Prof. Burbaud has nothing to disclose.
Dominique Guehl No disclosure on file
Bastien Ribot, PhD Mr. RIBOT has nothing to disclose.
Marc Deffains, PhD Mr. Deffains has nothing to disclose.
Brian Rutt No disclosure on file
Tritia Reina Yamasaki, MD, PhD, FAAN The institution of Dr. Yamasaki has received research support from Veteran's Affairs. The institution of an immediate family member of Dr. Yamasaki has received research support from Dept of Energy.
Lilia Turcios, PhD Dr. Turcios has nothing to disclose.
Johannah Stegemann, Other Ms. Stegemann has nothing to disclose.
Elena Ostrakhovitch, PhD Dr. Ostrakhovitch has nothing to disclose.
Saad Hulou, MD Dr. Hulou has received research support from University of Aleppo.
Ekaterina Rogaeva Ekaterina Rogaeva has nothing to disclose.
Negin Badihian, MD Dr. Badihian has nothing to disclose.
Nirubol Tosakulwong Nirubol Tosakulwong has nothing to disclose.
Stephen Weigand Stephen Weigand has nothing to disclose.
Farwa Ali, MD Dr. Ali has nothing to disclose.
Hugo Botha, MD Dr. Botha has received research support from NIH.
Heather Clark Heather Clark has received personal compensation for serving as an employee of Mayo Clinic. The institution of Heather Clark has received research support from NIH. Heather Clark has received publishing royalties from a publication relating to health care.
Julie Stierwalt The institution of Julie Stierwalt has received research support from NIH. Julie Stierwalt has received publishing royalties from a publication relating to health care. Julie Stierwalt has received publishing royalties from a publication relating to health care.
Rodolfo Savica, MD, PhD, FAAN The institution of Dr. Savica has received research support from ACADIA Pharmaceuticals, Inc.
Dennis W. Dickson, MD Dr. Dickson has nothing to disclose.
Jennifer Louise Whitwell, PhD Dr. Whitwell has nothing to disclose.
Keith A. Josephs, Jr., MD, FAAN Dr. Josephs has nothing to disclose.
Janice Robertson Janice Robertson has nothing to disclose.
George Kannarkat Dr. Kannarkat has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Guidepoint Global.
Alice Chen-Plotkin, MD Dr. Chen-Plotkin has received intellectual property interests from a discovery or technology relating to health care.
Rebecca Kaytelynn Zack, Other Miss Zack has nothing to disclose.
Robert *use 392746 Skrinak No disclosure on file
James F. Morley, MD,PhD Dr. Morley has nothing to disclose.
Roseanne Davila-Rivera Ms. Davila-Rivera has nothing to disclose.
Sanaz Arezoumandan Ms. Arezoumandan has nothing to disclose.
Katherine Dorfman Ms. Dorfman has nothing to disclose.
Kelvin Luk No disclosure on file
Daniel Weintraub Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Clintrex. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scion. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunovion. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Modality.ai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CuraSen. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boehringer Ingelheim. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorder Society. The institution of Daniel Weintraub has received research support from NIH. The institution of Daniel Weintraub has received research support from Fox Foundation. The institution of Daniel Weintraub has received research support from IPMDS. Daniel Weintraub has received intellectual property interests from a discovery or technology relating to health care.
Thomas F. Tropea, DO Dr. Tropea has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Bial. The institution of Dr. Tropea has received research support from NINDS. The institution of Dr. Tropea has received research support from Parkinson Foundation. The institution of Dr. Tropea has received research support from Michael J Fox Foundation.
Edward Lee The institution of Edward Lee has received research support from NIH.
Virginia Lee, PhD Virginia Lee, PhD has nothing to disclose.
David Irwin, MD The institution of Dr. Irwin has received research support from NIH. The institution of Dr. Irwin has received research support from Prevail. The institution of Dr. Irwin has received research support from Passage Bio. The institution of Dr. Irwin has received research support from Alector. The institution of Dr. Irwin has received research support from Transposon. The institution of Dr. Irwin has received research support from Denali.
Rizwan Akhtar, MD The institution of Dr. Akhtar has received research support from Vanqua Bio.