2014 Annual Meeting | Parkinson's Disease: Genetics and Epidemiology

Date Tuesday 04/29/14

Time 03:15 PM - 05:00 PM Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program is not expected to be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Topic(s) Movement Disorders

CME Available No CME available

Event Timeline
03:15 PM - 05:00 PM	Abstract	001 - Mutations in the GCH1 Gene Are Associated with Parkinson Disease Niccolò Mencacci
03:15 PM - 05:00 PM	Abstract	002 - Age Specific Penetrance of the LRRK2 G2019S Mutation in the Michael J Fox Ashkenazi Jewish (AJ) LRRK2 Consortium Karen S. Marder, MD, MPH, FAAN
03:15 PM - 05:00 PM	Abstract	003 - RER1: A Novel Regulator of Alpha-Synuclein Nikolaus McFarland, MD, PhD, FAAN
03:15 PM - 05:00 PM	Abstract	004 - Apolipoprotein A1 levels are Associated with APOA1 Promoter Variation and Influence Parkinson's Disease Risk Christine R. Swanson, PhD
03:15 PM - 05:00 PM	Abstract	005 - Prevalence and Predictors of Anti-Parkinson Drug Use in a Nationally Representative Sample of Medicare Beneficiaries, 2006-2010 Nabila Dahodwala, MD, FAAN
03:15 PM - 05:00 PM	Abstract	006 - Serum Cholesterol, Statin, and Parkinson's Risk in the Atherosclerosis Risk in Communities (ARIC) Study Xuemei Huang, MD, PhD
03:15 PM - 05:00 PM	Abstract	007 - Time trends in the incidence of parkinsonism and Parkinson disease in Olmsted County, Minnesota over thirty years Rodolfo Savica, MD, PhD, FAAN

Faculty Disclosures
Roy Alcalay, MD	Dr. Alcalay has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genzyme/Sanofi. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Gain Therapeutics. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Vanqua Bio. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Takeda. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biohaven. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Capsida. Dr. Alcalay has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Servier. The institution of Dr. Alcalay has received research support from Michael J. Fox Foundation. The institution of Dr. Alcalay has received research support from Parkinson's Foundation. The institution of Dr. Alcalay has received research support from Silverstein Foundation. Dr. Alcalay has received personal compensation in the range of $50,000-$99,999 for serving as a Consultant with Parkinson's Foundation.
Joshua M. Shulman, MD, PhD, FAAN	Dr. Shulman has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Dr. Shulman has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Helis Medical Foudation. The institution of Dr. Shulman has received research support from National Institutes of Health.
Brandon R. Grossardt, MS	No disclosure on file
Kailash P. Bhatia, MD, FAAN	Dr. Bhatia has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Ipsen. Dr. Bhatia has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Mitsubishi. Dr. Bhatia has received personal compensation in the range of $10,000-$49,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for MDS . The institution of Dr. Bhatia has received research support from EU Horizon 2020.
Laurie J. Ozelius, PhD	The institution of Dr. Ozelius has received research support from NIH. Dr. Ozelius has received intellectual property interests from a discovery or technology relating to health care.
Gianni Pezzoli, MD	Dr. Pezzoli has nothing to disclose.
Nabila Dahodwala, MD, FAAN	Dr. Dahodwala has received personal compensation in the range of $0-$499 for serving as a Consultant for Genetech. Dr. Dahodwala has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Mediflix. Dr. Dahodwala has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Dr. Dahodwala has received personal compensation in the range of $5,000-$9,999 for serving as an Expert Witness for Post and Schell. Dr. Dahodwala has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for O'Brien & Ryan, LLP. The institution of Dr. Dahodwala has received research support from AbbVie. The institution of Dr. Dahodwala has received research support from Medtronic.
Alexis Brice, MD	Dr. Brice has received personal compensation in the range of $100,000-$499,999 for serving as an officer or member of the Board of Directors for ICM.
Nikolaus McFarland, MD, PhD, FAAN	Dr. McFarland has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sutter Health. The institution of Dr. McFarland has received research support from NIH. Dr. McFarland has received publishing royalties from a publication relating to health care.
Cyrus P. Zabetian, MD	The institution of Dr. Zabetian has received research support from American Parkinson Disease Association. The institution of Dr. Zabetian has received research support from Department of Veterans Affairs. The institution of Dr. Zabetian has received research support from NIH. Dr. Zabetian has a non-compensated relationship as a Member, Scientific Advisory Council with Lewy Body Dementia Association that is relevant to AAN interests or activities.
	No disclosure on file
John W. Roberts, MD	No disclosure on file
Ali Samii, MD, FRCP	Dr. Samii has nothing to disclose.
James B. Leverenz, MD, FAAN	Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia. Dr. Leverenz has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Leverenz has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Eisai.
Susan B. Bressman, MD, FAAN	The institution of Dr. Bressman has received research support from Michael J Fox Foundation . The institution of Dr. Bressman has received research support from NIH .
Huw R. Morris, MD, PhD	Dr. Morris has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Dr. Morris has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Biogen. Dr. Morris has received personal compensation in the range of $50,000-$99,999 for serving as an Expert Witness for Personal injury / Negligence cases. The institution of Dr. Morris has received research support from Parkinson's UK. The institution of Dr. Morris has received research support from Michael J Fox Foundartion. The institution of Dr. Morris has received research support from Cure Parkinson's Trust. The institution of Dr. Morris has received research support from PSP Association. The institution of Dr. Morris has received research support from CBD Solutions. The institution of Dr. Morris has received research support from Drake Foundation. The institution of Dr. Morris has received research support from Medical Research Council. Dr. Morris has received intellectual property interests from a discovery or technology relating to health care. Dr. Morris has a non-compensated relationship as a Scientific Advisory Board with Cure PSP that is relevant to AAN interests or activities. Dr. Morris has a non-compensated relationship as a Scientific Advisory Board with Parkinson's UK that is relevant to AAN interests or activities.
Nir Giladi, MD, FAAN	Dr. Giladi has received personal compensation in the range of $0-$499 for serving as a Consultant for Sionara. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for NeuroDerm. Dr. Giladi has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Pharma2B. Dr. Giladi has stock in Vibrant. Dr. Giladi has stock in Lysosomal Therapeutics . The institution of Dr. Giladi has received research support from The Michael J Fox Foundation. The institution of Dr. Giladi has received research support from The National Parkinson Foundation. The institution of Dr. Giladi has received research support from The European Union . The institution of Dr. Giladi has received research support from The Israel Science Foundation. The institution of Dr. Giladi has received research support from Biogen . The institution of Dr. Giladi has received research support from Ionis. The institution of Dr. Giladi has received research support from Sieratzki Family Foundation . The institution of Dr. Giladi has received research support from The Aufzien Academic Center in Tel-Aviv University.
Jens Volkmann, MD	No disclosure on file
Paul Krack, MD	No disclosure on file
Nicholas W. Wood	No disclosure on file
Walter A. Rocca, MD, MPH	The institution of Dr. Rocca has received research support from National Institute on Aging - NIH. The institution of Dr. Rocca has received research support from National Heart, Lung, and Blood Institute - NIH.
Rachel J. Saunders-Pullman, MD	The institution of Dr. Saunders-Pullman has received research support from NIH, Bigglesworth Family Foundation, Empire Clinical Research Investigatory Program.
John Q. Trojanowski, MD, PhD	Dr. Trojanowski has nothing to disclose.
Andrew J. Lees, MD, FRCP	Dr. Lees has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Britannia. Dr. Lees has received personal compensation in the range of $5,000-$9,999 for serving as a Speaker with Bial Pharma.
James H. Bower, MD, MSc, FAAN	The institution of Dr. Bower has received research support from Abbvie.
Ioannis U. Isaias, MD	Dr. Isaias has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Newronika. Dr. Isaias has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Medtronic. Dr. Isaias has stock in Newronika. Dr. Isaias has received research support from Fondazione Grigioni per il Morbo di Parkinson. The institution of Dr. Isaias has received research support from Fresco Parkinson Institute Italia Onlus. The institution of Dr. Isaias has received research support from Deutsche Forschungsgemeinschaft.
Honglei Chen, MD, PhD, FAAN	The institution of Dr. Chen has received research support from NIH, . The institution of Dr. Chen has received research support from DoD. The institution of Dr. Chen has received research support from Parkinson's Foundation. The institution of Dr. Chen has received research support from MSU GE and Gibby vs. Parky project.
Daniel Weintraub	Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Clintrex. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Eisai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sage. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Scion. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Signant. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sunovion. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Modality.ai. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Cerevel. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for CuraSen. Daniel Weintraub has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Takeda. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Boehringer Ingelheim. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche. Daniel Weintraub has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Acadia. Daniel Weintraub has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorder Society. The institution of Daniel Weintraub has received research support from NIH. The institution of Daniel Weintraub has received research support from Fox Foundation. The institution of Daniel Weintraub has received research support from IPMDS. Daniel Weintraub has received intellectual property interests from a discovery or technology relating to health care.
Andrew Singleton	An immediate family member of Andrew Singleton has received personal compensation for serving as an employee of GeneDx. Andrew Singleton has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Nature Partner Journals Parkinson Disease. Andrew Singleton has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Movement Disorders Journal. An immediate family member of Andrew Singleton has stock in GeneDx. The institution of Andrew Singleton has received research support from Michael J Fox Foundation. Andrew Singleton has received intellectual property interests from a discovery or technology relating to health care. Andrew Singleton has received intellectual property interests from a discovery or technology relating to health care.
Paulo J. Alegria, MD	No disclosure on file
Jacqueline Rick	No disclosure on file
Rachel Goldmann Gross, MD	No disclosure on file
Thomas H. Mosley, PhD	No disclosure on file
Mingxin Tang, PhD	No disclosure on file
Alice Chen-Plotkin, MD	Dr. Chen-Plotkin has received intellectual property interests from a discovery or technology relating to health care.
Deborah Raymond	The institution of Ms. Raymond has received research support from NIH.
Kin-Ying Mok, MBBS, MRCP	No disclosure on file
Henry Houlden	No disclosure on file
Xuemei Huang, MD, PhD	No disclosure on file
Allison Wright Willis, MD	Dr. Wright Willis has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Pharmacoepidemiology and Drug Safety. Dr. Wright Willis has received personal compensation in the range of $0-$499 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for JAMA Neurology. The institution of Dr. Wright Willis has received research support from NIH. The institution of Dr. Wright Willis has received research support from NIA. The institution of Dr. Wright Willis has received research support from Biogen. The institution of Dr. Wright Willis has received research support from Parkinson Foundation. The institution of Dr. Wright Willis has received research support from Arcadia.
Lorraine N. Clark, PhD	No disclosure on file
Pinky Agarwal, MD, FAAN	Dr. Agarwal has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Supernus. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Acadia Pharmaceuticals Inc. Dr. Agarwal has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Amneal. Dr. Agarwal has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Neurocrine. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Regenx Bio . Dr. Agarwal has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Cerevel Therapeutics. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Mitsubishi Tanabe Pharma. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Avion Pharma. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving as a Consultant for AbbVie. Dr. Agarwal has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acadia. Dr. Agarwal has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Supernus. Dr. Agarwal has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Kyowa Kirin. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Acorda. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Amneal. Dr. Agarwal has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for AbbVie. An immediate family member of Dr. Agarwal has stock in ACTINIUM PHARMACEUTICALS INC. An immediate family member of Dr. Agarwal has stock in ALDEYRA THERAPEUTICS INC. An immediate family member of Dr. Agarwal has stock in Aquestive Therapeutics. An immediate family member of Dr. Agarwal has stock in Corcept Therapeutics. An immediate family member of Dr. Agarwal has stock in Catalyst Pharmaceuticals. An immediate family member of Dr. Agarwal has stock in Curis Inc. An immediate family member of Dr. Agarwal has stock in Citius Pharmaceuticals. An immediate family member of Dr. Agarwal has stock in Fortress Biotech. An immediate family member of Dr. Agarwal has stock in Gevo Inc. An immediate family member of Dr. Agarwal has stock in G1 Therapeutics. An immediate family member of Dr. Agarwal has stock in Marinus Pharnmaceuticals. An immediate family member of Dr. Agarwal has stock in OVID Therapeutics. An immediate family member of Dr. Agarwal has stock in Pieris Pharmaceuticals. An immediate family member of Dr. Agarwal has stock in TG Therapeutics. An immediate family member of Dr. Agarwal has stock in ATYR PHARMA INC . An immediate family member of Dr. Agarwal has stock in ASSERTIO HOLDINGS INC . An immediate family member of Dr. Agarwal has stock in BLUEBIRD BIO INC . An immediate family member of Dr. Agarwal has stock in CORVUS PHARMACEUTICALS INC . An immediate family member of Dr. Agarwal has stock in GALECTO INC . An immediate family member of Dr. Agarwal has stock in GLYCOMIMETICS INC. An immediate family member of Dr. Agarwal has stock in Zevra Therapeutics. An immediate family member of Dr. Agarwal has stock in LAVA THERAPEUTICS . An immediate family member of Dr. Agarwal has stock in MEREO BIOPHARMA GROUP PLC. An immediate family member of Dr. Agarwal has stock in OVID THERAPEUTICS INC . An immediate family member of Dr. Agarwal has stock in PHASEBIO PHARMACEUTICALS INC. An immediate family member of Dr. Agarwal has stock in PROTALIX BIOTHERAPEUTICS INC. An immediate family member of Dr. Agarwal has stock in TERNS PHARMACEUTICALS INC. An immediate family member of Dr. Agarwal has stock in VIKING THERAPEUTICS INC. Dr. Agarwal has stock in WAVE LIFE SCIENCES LTD. An immediate family member of Dr. Agarwal has stock in Puma Biotech. An immediate family member of Dr. Agarwal has stock in Xeris Biopharma. An immediate family member of Dr. Agarwal has stock in Tonix Pharma. An immediate family member of Dr. Agarwal has stock in Spruce Biosciences. An immediate family member of Dr. Agarwal has stock in Cassava Sciences. An immediate family member of Dr. Agarwal has stock in ProQr Therapeutics. An immediate family member of Dr. Agarwal has stock in Mind Medicine. An immediate family member of Dr. Agarwal has stock in Lyra Therapeutics. An immediate family member of Dr. Agarwal has stock in Larimer Therapeutics. An immediate family member of Dr. Agarwal has stock in Lantern Pharma. An immediate family member of Dr. Agarwal has stock in Cue Biopharma. An immediate family member of Dr. Agarwal has stock in Caribou Biosciences. An immediate family member of Dr. Agarwal has stock in Capricor Therapeutics. An immediate family member of Dr. Agarwal has stock in Black Diamond Therapeutics. An immediate family member of Dr. Agarwal has stock in Applied Therapeutics. An immediate family member of Dr. Agarwal has stock in Amylyx Pharma. An immediate family member of Dr. Agarwal has stock in Palisade Bio. An immediate family member of Dr. Agarwal has stock in Passage Bio. An immediate family member of Dr. Agarwal has stock in Sutro Biopharma. An immediate family member of Dr. Agarwal has stock in Karyopharma. An immediate family member of Dr. Agarwal has stock in Inozyme Pharma. An immediate family member of Dr. Agarwal has stock in Oncolytic Biotech. An immediate family member of Dr. Agarwal has stock in Pyxis Oncology. An immediate family member of Dr. Agarwal has stock in Vistagen Therapeutics. An immediate family member of Dr. Agarwal has stock in Tscan Therapeutics. The institution of Dr. Agarwal has received research support from Biogen . The institution of Dr. Agarwal has received research support from CHDI Foundation. The institution of Dr. Agarwal has received research support from Eli Lilly. The institution of Dr. Agarwal has received research support from MJ Fox. The institution of Dr. Agarwal has received research support from Roche . The institution of Dr. Agarwal has received research support from Supernus. The institution of Dr. Agarwal has received research support from Nova Nordisc. The institution of Dr. Agarwal has received research support from Sun Pharma. The institution of Dr. Agarwal has received research support from Inhibikase.
Rodolfo Savica, MD, PhD, FAAN	The institution of Dr. Savica has received research support from ACADIA Pharmaceuticals, Inc.
J. E. Ahlskog, MD, PhD	Dr. Ahlskog has received publishing royalties from a publication relating to health care.
Karen S. Marder, MD, MPH, FAAN	Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Genentech. Dr. Marder has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Parkinson's Foundation . Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for CHDI. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for PTC therapeutics. Dr. Marder has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for Springer LTD. The institution of Dr. Marder has received research support from Vaccinex. The institution of Dr. Marder has received research support from Genentech. The institution of Dr. Marder has received research support from Triplet Therapeutics. The institution of Dr. Marder has received research support from Prilenia.
Howard I. Hurtig, MD	No disclosure on file
Christine R. Swanson, PhD	No disclosure on file
Niccolò Mencacci	No disclosure on file
Joshua Hersheson, MBBS	No disclosure on file
Maria Stamelou, MD, PhD	No disclosure on file
Alvaro Alonso	No disclosure on file
Anna Lena Zecchinelli	No disclosure on file
Alastair J. Noyce, MBBS	Dr. Noyce has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for uMed. Dr. Noyce has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for AbbVie. Dr. Noyce has received personal compensation in the range of $10,000-$49,999 for serving on a Scientific Advisory or Data Safety Monitoring board for AstraZeneca. Dr. Noyce has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Charco NeuroTech. Dr. Noyce has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Alchemab. Dr. Noyce has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for MDS. Dr. Noyce has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for BIAL. Dr. Noyce has received personal compensation in the range of $10,000-$49,999 for serving as an officer or member of the Board of Directors for Oxford Pharmagenesis. Dr. Noyce has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for AstraZeneca. The institution of Dr. Noyce has received research support from Solvemed. The institution of Dr. Noyce has received research support from Alchemab.
Suzanne Lesage, PhD	Dr. Lesage has nothing to disclose.
Kavita Sail, PhD	No disclosure on file
Yash Jalundhwala, PhD	Dr. Jalundhwala has received personal compensation for serving as an employee of AbbVie . An immediate family member of Dr. Jalundhwala has received personal compensation for serving as an employee of AbbVie . Dr. Jalundhwala has received stock or an ownership interest from AbbVie.
Greg Mytyk	No disclosure on file