2014 Annual Meeting | MS and CNS Inflammatory Disease: Biomarkers and Therapeutic Mechanisms

Date Thursday 05/01/14

Time 01:00 PM - 02:45 PM Add To Calendar

Session Format This program will be presented both in-person and online

On Demand This program is not expected to be available in the meeting's On Demand product.

Event Type Scientific Platform Session

Topic(s) Multiple Sclerosis

CME Available No CME available

Event Timeline
01:00 PM - 02:45 PM	Abstract	001 - Following anti-CD20 Treatment Immune-Competent B Cells Reoccur in Bone Marrow and Spleen Before They Can Be Detected in Peripheral Blood Martin Weber, MD
01:00 PM - 02:45 PM	Abstract	003 - Increased CSF level of monocyte/microgrial activation maker in progressive- multiple sclerosis Mika Komori
01:00 PM - 02:45 PM	Abstract	004 - S1P Receptor Modulation by Fingolimod Promotes Human Oligodendrocyte Progenitor Cell Differentiation through Cell-Autonomous and Non-Cell Autonomous Mechanisms via ERK1/2 and p38MAPK Activation Qiao Ling Cui, MD
01:00 PM - 02:45 PM	Abstract	005 - Chitinase 3-like 1 and Chitinase 3-like 2 as Diagnostic and Prognostic Biomarkers of Multiple Sclerosis Eric Thouvenot, MD, PhD
01:00 PM - 02:45 PM	Abstract	006 - Dimethyl fumarate utilizes Nrf2-independent and Nrf2-dependent pathways for immune modulation Scott S. Zamvil, MD, PhD, FAAN
01:00 PM - 02:45 PM	Abstract	007 - Antibodies against the Inward Rectifying Potassium Channel KIR4.1 precede the onset of Multiple Sclerosis Viola Biberacher

Faculty Disclosures
Amit Bar-Or, MD, FRCPC	Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Roche Genentech. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Janssen/Actelion. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Atara Biotherapeutics. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biogen. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for BMS. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merk/EMD Serono. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Sanofi-Genzyme. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Atara Biotherapeutics. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche/Genentech. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Merck/EMD Serono. Dr. Bar-Or has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Sanofi/Genzyme. The institution of Dr. Bar-Or has received research support from Novartis. The institution of Dr. Bar-Or has received research support from Biogen. The institution of Dr. Bar-Or has received research support from Roche/Genentech. The institution of Dr. Bar-Or has received research support from Merck/EMD Serono.
Bibiana Bielekova, MD, FAAN	Dr. Bielekova has received research support from National Institutes of Allergy and Infectious Diseases. Dr. Bielekova has received intellectual property interests from a discovery or technology relating to health care. Dr. Bielekova has received publishing royalties from a publication relating to health care.
Pierre Labauge, MD	Dr. Labauge has nothing to disclose.
Qiao Ling Cui, MD	No disclosure on file
	No disclosure on file
Scott S. Zamvil, MD, PhD, FAAN	Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Alexion. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving on a Speakers Bureau for Genzyme. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as an Editor, Associate Editor, or Editorial Advisory Board Member for AAN. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as a Advisory Board with Genzyme. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as a Advisory Board with Genentech. Dr. Zamvil has received personal compensation in the range of $500-$4,999 for serving as a Advisory Board with Alexion.
Timothy L. Vollmer, MD, FAAN	The institution of Dr. Vollmer has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Biogen IDEC. The institution of Dr. Vollmer has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Genentech/Roche. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Siranax. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Celgene. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for EMD Serono. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Bristol Meyers Squib. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Viela Bios. The institution of Dr. Vollmer has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Novartis. The institution of Dr. Vollmer has received research support from Rocky Mountain MS Center. The institution of Dr. Vollmer has received research support from Biogen. The institution of Dr. Vollmer has received research support from Actelion. The institution of Dr. Vollmer has received research support from Genentech/Roche. The institution of Dr. Vollmer has received research support from Anokion. The institution of Dr. Vollmer has received research support from TG Therapeutics.
Stuart H. Isaacson, MD, FAAN	The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Acadia. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Sunovion. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for acorda. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Supernus. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Neurocrine. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Kyowa. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for adamas. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Lundbeck. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Teva. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Neuroderm. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Abbvie. The institution of Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for amneal. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Teva. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Neurocrine. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for adamas. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Lundbeck. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Supernus. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acadia. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Acorda. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Amneal. Dr. Isaacson has received personal compensation in the range of $10,000-$49,999 for serving on a Speakers Bureau for Abbvie.
Dorothea A. Buck, MD	No disclosure on file
Bernhard Hemmer, MD	No disclosure on file
Paul Matthews, MD	No disclosure on file
Olivier Casez, MD	Dr. Casez has nothing to disclose.
John G. Whitesides	John G. Whitesides has received personal compensation for serving as an employee of UCB. John G. Whitesides has received stock or an ownership interest from UCB.
Giovanni Castelnovo	No disclosure on file
William Camu, MD	No disclosure on file
Eric Thouvenot, MD, PhD	Dr. Thouvenot has received personal compensation in the range of $0-$499 for serving as a Consultant for Biogen. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Biologix FZCo.. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Merck. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving as a Consultant for Teva. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving as a Consultant for HEALTHME. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Roche. Dr. Thouvenot has received personal compensation in the range of $500-$4,999 for serving on a Scientific Advisory or Data Safety Monitoring board for Novartis. The institution of Dr. Thouvenot has received research support from Biogen. The institution of Dr. Thouvenot has received research support from Novartis. The institution of Dr. Thouvenot has received research support from Roche.
Ulf Schulze Topphoff	Ulf Schulze Topphoff has received personal compensation for serving as an employee of Novartis Pharma GmbH.
Robert H. Scannevin, PhD	No disclosure on file
Andrew Blake	No disclosure on file
Michel Varrin-Doyer	No disclosure on file
Lucas Schirmer, MD	No disclosure on file
Danielle E. Harlow, PhD	No disclosure on file
Viola Biberacher	No disclosure on file
Martin Weber, MD	Dr. Weber has nothing to disclose.
Sean Selva	No disclosure on file
Mika Komori	Mika Komori has received personal compensation for serving as an employee of Eli Lilly K.K..
Jack P. Antel, MD, FAAN	Dr. Antel has received personal compensation in the range of $5,000-$9,999 for serving on a Scientific Advisory or Data Safety Monitoring board for sanofi, roche, biogen, wave,nervgen. The institution of Dr. Antel has received research support from Novartis canada bristol myers squib. Dr. Antel has a non-compensated relationship as a past president with ACTRIMS that is relevant to AAN interests or activities.
Jimmy Schiemann	No disclosure on file