June 22, 2015: Benign Pathology, Catastrophic Location

Interested in submitting an E-Pearl?
Brought to you by the Residents & Fellows Section of Neurology.

June 22, 2015

Benign Pathology, Catastrophic Location

Colloid cysts are a rare developmental malformation that most commonly occur in the third ventricle at the level of the foramen of Monro. Although histologically benign and typically asymptomatic, colloid cysts can cause increased intracranial pressure and present with headache, papilledema, neurocognitive changes and occasionally gait abnormalities. Rarely, sudden death can occur from acute obstruction of the ventricular system. Most often colloid cysts are hyperintense on T1 and hypointense on T2-weighted MRI images. Treatment options include open microsurgical resection and more recently endoscopic resection


  1. Hadley D. Colloid cyst of the IIIrd ventricle. Journal of Neurology, Neurosurgery & Psychiatry 2002; 72 (Suppl 2): ii15.
  2. Yadav YR, Parihar V, Pande SE, Namdev H. Endoscopic management of colloid cysts. Journal of Neurological Surgery Part A: Central European Neurosurgery 2014; 75: 376-380.

Submitted by Ahmed Yassin MD, Academic chief resident, Department of Neurology, University of Texas Medical Branch. Galveston, TX.

Disclosures: Dr. Yassin reports no disclosures.

For more clinical pearls and other articles of interest to neurology trainees, visit Neurology. Listen to this week's Neurology Podcast.


Forgot password?

**Due to required system maintenance on, some functions may be unavailable Friday, 12/15/2017, through Monday, 12/18/2017. Thank you for your patience.**