February 13, 2014: Neurapraxia

Interested in submitting an E-Pearl?
Brought to you by the Residents & Fellows Section of Neurology®.

February 13, 2014

Neurapraxia was first described in 1942 by Dr. Seddon who also named it "transient block" (1). It is the mildest form of peripheral nerve injury, characterized as transient loss of motor or sensory conduction without nerve structural changes.  The motor and proprioceptive fibers are affected more often.  Usually the nerves regain function in days to weeks. Cold, ischemia, compression, and blunt injury are common causes. The exact mechanism is unknown but lamellar separation of myelin sheath was found to be related (2).


  1. Seddon HJ. A classification of nerve injuries. Br Med J 1942; 2:237-239.
  2. Yan AH, Hui L, Shi Y, Ren Z, Xie L. The study of facial neurapraxia. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2000; 14: 364-365.

Submitted by Lingling Rong, MD, Resident Physician, University of South Florida 

Disclosures: Dr. Rong is a junior member of the AAN

For more clinical pearls and other articles of interest to neurology trainees, visit Neurology ®. Listen to this week's Neurology Podcast.


Forgot password?

**Due to required system maintenance on, some functions may be unavailable Friday, 12/15/2017, through Monday, 12/18/2017. Thank you for your patience.**