August 22, 2016: Transient cerebral arteriopathy in children

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August 22, 2016

Transient cerebral arteriopathy in children

Transient cerebral arteriopathy is the most common type of arteriopathy in children presenting with acute ischemic strokes. It manifests as large and medium vessel vasculopathy, triggered most commonly by infections, usually viral (varicella zoster virus, parvovirus B19, and cytomegalovirus), and/or inflammation. Diagnosis is by vascular imaging (MRA and/or cerebral angiogram) showing unilateral stenosis of the distal internal carotid artery or proximal segments of the anterior or middle cerebral arteries. The vasculopathy resolves within 6 months after the initial stroke. The benefits of anticoagulant and/or anti-inflammatory therapy remain uncertain.

  1. Sébire G. Transient cerebral arteriopathy in childhood. Lancet 2006; 368: 8-10.
  2. Sébire G, Fullerton H, Riou E, deVeber G. Toward the definition of cerebral arteriopathies of childhood. Current opinion in pediatrics 2004; 16: 617-22.

Submitted by Aravindhan Veerapandiyan, MBBS, Pediatric Neurology Fellow, Department of Neurology, Division of Child Neurology, Rutgers University - New Jersey Medical School.

Dr. Veerapandiyan reports no disclosures.


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