December 10, 2015: Subcortical Aphasia (SA)

Interested in submitting an E-Pearl?
Brought to you by the Residents & Fellows Section of Neurology.

DECEMBER 10, 2015

Subcortical Aphasia (SA

Aphasia can occur from lesions of subcortical structures including the basal ganglia, anterolateral nuclei of thalamus and peri-capsular white matter of the language-dominant hemisphere; some data suggest that hypoperfusion of the adjacent cortex is the underlying process. Features distinguishing subcortical from cortical aphasias include reduced voice volume, articulation impairment (e.g. "wabbit" for rabbit), and the presence of echolalia. Oral reading, word comprehension, and repetition are typically preserved and phonemic paraphasias are uncommon. 

  1. Mega, Michael S, Alexander, Michael P. Subcortical Aphasia: the core profile of capsulostriatal infarction.  Neurology 1994; 44: 1824-1829.
  2. Hillis AE, Wityk RJ, Barker PB, et al. Subcortical aphasia and neglect in acute stroke: the role of cortical hypoperfusion. Brain 2002; 125: 1094.

Submitted by Rachel Dayno, Medical Student, Temple University School of Medicine and Kandan Kulandaivel, MD, Department of Neurosciences, Abington Hospital.

Disclosures: Rachel Dayno and Dr. Kulandaivel report no disclosures.

For more clinical pearls and other articles of interest to neurology trainees, visit Neurology. Listen to this week's Neurology Podcast.



Forgot password?

**Due to required system maintenance on, some functions may be unavailable Friday, 12/15/2017, through Monday, 12/18/2017. Thank you for your patience.**