Abstract Details

Title Real-World Assessment of DBS Outcomes Using a 16-Contact Device Capable of Multiple Independent Current Control

Topic Movement Disorders

Presentation(s) P1 - Poster Session 1 (12:00 PM-1:00 PM)

Poster/Presentation
Number 3-007

Objective This report will assess the real-world clinical outcomes associated with the use of a 16-contact device capable of Multiple Independent Current Control (MICC).

Background Deep Brain Stimulation (DBS) is a safe and effective treatment for motor signs and fluctuations associated with Parkinson’s disease (PD) and has been fully substantiated as such by several randomized controlled trials. Moreover, motor improvement following DBS has been shown to be sustained for up to 10 years (Castrioto A., et al. Arch Neurol. 2011 Dec;68(12):1550-6). Retrospective studies provide a relatively quick and cost-effective means to obtain data regarding various types of patient outcomes when devices are being used per standard-of-care in the real-world clinical setting.

Design/Methods This is an observational clinical study conducted in the United States of DBS patient outcomes (ClinicalTrials.gov Identifier: NCT03664609) based on retrospective chart review. Patients assessed in this evaluation are implanted with a DBS system (Vercise, Boston Scientific) capable of MICC for use in the treatment of the symptoms of Parkinson’s disease. Data related to disease state, motor function, and overall quality of life are collected. Additionally, reduction in anti-parkinsonian medications usage is also assessed.

Results Study data is currently still being collected, and the analyzed results will be presented.

Conclusions This on-going observational study will serve to add to the compendium of data examining real-world outcomes in patients implanted with DBS system capable of Multiple Independent Current Control.

Authors/Disclosures
Corneliu C. Luca, MD (University of Miami) PRESENTER	Dr. Luca has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Boston Scientific. Dr. Luca has received personal compensation in the range of $10,000-$49,999 for serving as a Consultant for Signant Health. Dr. Luca has received personal compensation in the range of $5,000-$9,999 for serving as a Consultant for Abbott.
Jonathan Jagid	Jonathan Jagid has received personal compensation in the range of $10,000-$49,999 for serving as an Expert Witness for Miami Dade County State Attorneys office. The institution of Jonathan Jagid has received research support from Boston Scientific.
Francesca Macaluso	No disclosure on file
Roshini Jain	Roshini Jain has received personal compensation for serving as an employee of Boston Scientific. Roshini Jain has received stock or an ownership interest from Boston Scientific.